About

Orgins of PCMI

The Psychiatric Cell Map Initiative was founded in 2017 by Jeremy Willsey, Matt State, and Nevan Krogan with the goals of (1) generating the necessary data and insights to bridge the knowledge gap between the genome and the clinic, and (2) establishing the infrastructure for efficient and sustained investigation well into the future.

Role Of PCMI at UCSF

The role of PCMI at UCSF is to leverage a gene-first, basic science approach to transform recent successes in gene discovery to an actionable understanding of psychiatric disorders.

PCMI Partners

We partner with organizations and individuals to achieve our aims through multiple ongoing collaborative efforts.

Cell Mapping In Psychiatry

PCMI seeks to map the physical, co-expression, and genetic interaction networks associated with the ever-growing list of psychiatric disorder-associated genes. This will be conducted in neurons and other relevant cell types derived from human induced pluripotent stem cells (iPSCs) using affinity purification mass spectrometry, CRISPR-based genetics techniques, RNA-Seq, and ChIP-Seq....

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PCMI seeks to map the physical, co-expression, and genetic interaction networks associated with the ever-growing list of psychiatric disorder-associated genes. This will be conducted in neurons and other relevant cell types derived from human induced pluripotent stem cells (iPSCs) using affinity purification mass spectrometry, CRISPR-based genetics techniques, RNA-Seq, and ChIP-Seq.